Esthe Pro Labo Inner Coat

Esthe Pro Labo Inner Coat – Beauty protection starts from within. Professional inner care with patented Nutrox Sun® and Japanese Akoya pearl powder.

The sun is a paradox. You need it for vitamin D, mood, and vital energy, but every minute in the sun triggers a cascade of processes that irreversibly change your skin. UV radiation generates free radicals, breaks down collagen, activates elastin-degrading enzymes, and stimulates melanin overproduction. The result? Pigmentation spots, loss of firmness, wrinkles, and uneven skin tone—what dermatology calls photoaging.

Esthe Pro Labo Inner Coat is a premium Japanese dietary supplement that protects the skin from UV damage from within, reaching areas no sunscreen can. It's not just protection. It's a complete inner & after-care system: it protects the skin from sun damage and simultaneously supports its regeneration after UV exposure. At the core of the formulation are two patented complexes: Nutrox Sun®, a clinically tested extract of citrus fruits and rosemary. This is complemented by Akoya pearl powder of Japanese origin, a premium ingredient with a thousand-year tradition in Japanese beauty care, which contains 17 amino acids and supports collagen production and skin tone uniformity.

40 capsules per pack

What does Inner Coat do for your skin?

Clinically-backed protection from UV damage. Nutrox Sun® demonstrably reduces skin redness after UV exposure and protects the collagen network from degradation by matrix metalloproteinases.

Slows photoaging — inhibition of MMP-1 and MMP-3 means less collagen and elastin breakdown. Result: skin retains firmness, elasticity, and smoothness for longer.

Systemic neutralization of free radicals. Polyphenols from citrus, rosemary, grapevine, hawthorn, and chamomile create multi-layered antioxidant protection that complements topical SPF products.

Reduces hyperpigmentation and evens skin tone. Pearl powder inhibits tyrosinase and gradually unifies skin tone without aggressive bleaching.

Supports collagen production from within — conchiolin from pearl powder stimulates fibroblasts and promotes the natural renewal of collagen fibers.

Strengthens the skin barrier — dokudami increases the expression of filaggrin, a key protein for maintaining skin hydration and resilience.
Soothes UV-induced inflammation — apigenin from chamomile and anti-inflammatory substances from dokudami help suppress inflammaging, chronic micro-inflammation that accelerates aging.

Nutrox Sun® is a patented mitochondrial DNA protector.
Nutrox Sun® is an exceptional citrus and rosemary extract containing three types of polyphenols with strong antioxidant properties. These effectively neutralize free radicals created by harmful UV radiation, thus preventing oxidative damage to cell membranes.

What do clinical studies say?
In a randomized, placebo-controlled crossover study published in a scientific journal (Journal of Photochemistry and Photobiology B: Biology), oral administration of Nutrox Sun® was shown to significantly reduce UV-induced skin redness (erythema). Specifically, while redness increased by 62.7% in the placebo group, it only increased by 41–44.7% in the Nutrox Sun® group, depending on the dose. After 72 hours, redness in the supplemented group almost returned to baseline values, while it remained elevated in the placebo group.
However, protection against sunburn is just the beginning. Studies have further shown that Nutrox Sun® inhibits the secretion of matrix metalloproteinases MMP-1 and MMP-3 — enzymes activated by UV radiation that degrade collagen and elastin in the dermis. Less MMP activity = less breakdown of the collagen network = slower photoaging. Treated subjects showed an improvement in skin wrinkling and elasticity compared to placebo.

Mechanism of action: Polyphenols from citrus (naringenin, hesperidin) and rosemary (carnosic acid, carnosol, rosmarinic acid) act synergistically as effective antioxidants — neutralizing free radicals generated by UV radiation before they can damage cellular structures. Simultaneously, they reduce lipoperoxidation — oxidative damage to lipids in cell membranes.

AG Herb MIX — The AG Herb MIX complex, composed of four herbs (hawthorn, Roman chamomile, vine leaf, and dokudami), provides anti-aging care from within and has a strong anti-glycation effect, increasing skin elasticity and lightening age pigmentation. 36Best
Glycation is a process in which sugars bind to proteins and lipids, forming so-called AGEs (advanced glycation end-products). These AGEs damage mitochondria, disrupt their function, and induce chronic oxidative stress, which triggers excessive melanin production. AG Herb MIX interrupts this chain.

Inner Coat does not use just any pearl powder. It contains powder from the nacre layer of the domestic Japanese Akoya pearl oyster (アコヤ貝). Akoya pearls are considered among the highest quality pearls in the world due to their exceptional whiteness and luster, and these qualities are reflected in the quality of the bioactive substances obtained from their nacre layer.
In Japanese and Chinese medicine, pearl powder has been used for thousands of years as a means for radiant, even, and youthful skin. And modern biochemistry explains why.
Collagen production support: Akoya nacre contains conchiolin, a protein composed of 17 amino acids that stimulates fibroblasts to produce collagen. Research published in scientific journals confirms that water-soluble components of pearl powder support skin tissue regeneration, angiogenesis (formation of new blood vessels), and accelerate the renewal of damaged skin.
Skin tone evening: Conchiolin and other bioactive components of pearl powder inhibit the activity of tyrosinase, an enzyme responsible for melanin production. The result is a gradual lightening of pigment spots and a more even, radiant skin tone. This is not about bleaching; it is about restoring the skin's natural radiance by suppressing excessive pigmentation. Antioxidant protection: The amino acids contained in pearl powder provide protection against oxidative stress and environmental pollutants, thus complementing the antioxidant action of Nutrox Sun® and AG Herb MIX.

Take 2 capsules daily with water. Do not exceed the recommended dosage.

Skin renews itself in cycles of approximately 28 days. For visible results in skin tone unification and overall improvement of skin quality, we recommend regular use for at least 8–12 weeks.

Food supplement. Not a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of reach of children. Scientific references in the text refer to published clinical and preclinical studies; individual results may vary.

Plant extract powder (citrus fruit extract, rosemary leaf extract) (manufactured in Spain), starch, mixed herbal extract powder (maltodextrin, dokudami, Atlantic hawthorn, Roman chamomile, grape leaves), hardened canola oil, nacre powder / HPMC

Warning
Not suitable for children, pregnant and breastfeeding women. Keep out of reach of children. Store at temperatures up to 25 °C away from direct sunlight. Read the ingredients carefully before use.