Founder and CEO of Pro Labo Holdings, one of Japan’s most influential wellness brands. Under his leadership, a network of more than 27,000 locations—including stores, clinics, and restaurants—has been established. His philosophy links inner health with outer beauty and is based on science-backed solutions that today shape the standards of the Japanese beauty and wellness industry.

A Japanese cell biologist and recipient of the 2016 Nobel Prize in Physiology or Medicine. He is best known for his discovery of the mechanisms of autophagy—the process by which cells break down and recycle their own damaged components. His research has shown that autophagy is essential for cell regeneration, disease prevention, and slowing the aging process.

A world-renowned expert on autophagy and professor at Osaka University. As a close collaborator of Nobel laureate Yoshinori Ohsumi, he applied insights into autophagy to research on human cells and discovered the LC3 protein, now a globally recognized marker of autophagy. Herb Zyme 113 Gran Pro by Esthe Pro Labo was developed under his expert supervision.

A Japanese physician specializing in internal medicine and hematology, he holds a Ph.D. from Kumamoto University. He currently serves as director of the Juraku Clinic in Kumamoto. His research focuses on mitochondrial function, bodily regeneration, and slowing the aging process. His approach integrates cell science, medicine, and long-term health care.

A dermatologist, researcher, and director of the Roppongi Skin Clinic in Tokyo with over twenty years of experience treating acne, scars, and pigmentation. Since 2001, she has been clinically testing her own method for treating depressed acne scars. Her expertise in skin regeneration led to her collaboration on the Nano Reverse Factor®️ technology for the EPIUS line.

An oncologist, epigeneticist, and scientific advisor for the development of Nano Reverse Factor®️ technology. He began his research at Tottori University and continued to advance it at UT Southwestern Medical Center in the United States. His work focuses on the relationship between cancer, aging, and microRNA. His research has helped bridge the gap between cutting-edge epigenetic research and skin regeneration care.

Founder and owner of Beauren Korea, the company behind the Miracletox and Cellstory brands. Under his leadership, the patented Microspear®️ technology was developed, designed to enhance the effectiveness of active ingredients in the skin. Together with his in-house scientific team, he is pushing the boundaries of Korean cosmetics and bringing the modern beauty industry to life with visible results.

CEO of the Japanese company Peu à beauté, which develops a new generation of luxury functional clothing. The products utilize far-infrared technology, in which special mineral fibers work with the body’s natural heat. The goal is to promote microcirculation, muscle recovery, collagen production, and overall body care.

CEO of Mizuho Brush Co., Ltd. and the face of the luxury brand SHAQUDA. He leads a company with over 140 years of tradition in the handcrafted production of Japanese brushes. Under his leadership, the company creates premium brushes for skincare, body care, makeup, and wellness, blending artisanal precision, tradition, and modern luxury.