Hana Olscher: the future of beauty, health, and longevity from China and Japan
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What I brought back from Japan and China: the future of beauty, health, and longevity
I spent the last month in Japan and China. It wasn't a vacation or a typical business trip. It was a journey to discover where the world of health, beauty, regeneration, and longevity is truly heading today.
During this trip, I attended expert seminars, visited laboratories and clinics, and met with scientists, physicians, and developers of cutting-edge technologies in the fields of longevity, autophagy, regenerative medicine, exosomes, cellular energy, and modern skincare.
One of the most powerful experiences was a personal meeting with Professor Tamotsu Yoshimori, one of the world's most renowned experts on autophagy. His work is a key pillar of modern autophagy research and builds on the discoveries of Professor Yoshinori Ohsumi, who received the Nobel Prize in Physiology or Medicine in 2016 for discovering the mechanisms of autophagy.
I had the opportunity to complete professional training focused on autophagy, cellular regeneration, and healthy aging. As a result, I brought back not just information, but a deeper understanding of what science is really addressing today.
And do you know what surprised me the most? Although we discussed the most modern technologies—exosomes, cellular energy, NAD+, Deazaflavin, or regenerative medicine—all the experts agreed on one fundamental idea: what matters most is not only what we add to our bodies. What matters most is the state our body is in.
Creating a healthy environment for cells first
The world today is full of new trends. Biohacking. Longevity. Exosomes. Peptides. NAD+. Stem cells. Social media is flooded with information on how to extend life, slow down aging, or improve the skin.
However, what I heard repeatedly in Japan was much deeper. If our cells are long-term exposed to oxidative stress, chronic inflammation, poor digestion, lack of sleep, or excessive physiological strain, their regenerative capacity is limited.
That is why the Japanese always start with the basics: quality nutrition, fermentation, healthy digestion, gut microbiome, support for natural detoxification processes, cellular energy, quality sleep, and protection of cells from oxidative stress. Only then do the most modern longevity technologies make the most sense.
Detoxification is not a buzzword
One of the topics that came up very frequently was the organism's ability to rid itself of unnecessary burden. Today, we are exposed to many environmental influences: processed foods, stress, polluted air, lack of sleep, as well as long-term physical overload.
Japanese experts therefore place great emphasis on supporting the body's natural detoxification mechanisms. It is not about aggressive cleanses or short-term diets. It is about the long-term support of functions that our body performs every day through the liver, intestines, kidneys, lymphatic system, and other organs.
This is where true prevention begins. Because if an organism is burdened long-term, it cannot fully utilize quality food supplements or modern technologies.
Fermentation as the foundation of Japanese health philosophy
Another very strong topic was fermentation. In Japan, fermentation is not a trend. It has been a part of the culture for generations.
Modern research confirms that fermentation can support the bioavailability of certain nutrients and contribute to the balance of the gut environment. That is exactly why fermented products such as Herbzyme 113, Zakuro, or other Esthe Pro Labo fermented beverages are an important part of the Inner Beauty philosophy.
They are not intended only for short-term use. They are part of daily body care. Because health starts in the gut much more than most people realize. If digestion, nutrient absorption, and the gut environment are not functioning, regeneration, immunity, energy, and often even skin quality cannot function correctly either.
Autophagy is not an Instagram trend
In recent years, autophagy has been discussed very frequently. It is often associated with fasting, biohacking, or simple advice on social media.
However, after meeting with autophagy experts, I realized how complex and fascinating a process it actually is. Autophagy is not something that simply turns on after a few hours without food. It is a natural mechanism of cellular renewal, during which the cell recognizes damaged or unnecessary parts and recycles them. We can imagine it as the cells' internal cleaning system.
When autophagy works properly, cells can more effectively renew themselves and maintain their quality. However, its activity naturally declines with age. That is precisely why autophagy is considered one of the most important biological mechanisms related to healthy aging, vitality, and longevity today.
Its efficiency, however, depends on many factors: quality of nutrition, cellular energy, mitochondrial function, quality of sleep, level of oxidative stress, hormonal balance, and the overall state of the organism. This is why leading experts today do not view autophagy as a short-term dietary strategy, but as part of long-term health care, regeneration, and healthy aging.
Cellular energy and Deazaflavin
Every cell in our body needs energy. This energy is produced by mitochondria. Mitochondria determine how well we regenerate, how our brain, immunity, muscles, and skin function. Yet, their performance declines with age.
That is why scientists are now intensively focusing on NAD+ metabolism, which is essential for cellular energy production. Deazaflavin is currently receiving significant attention as well, being researched for its relationship to cellular energy metabolism and healthy mitochondrial function. The field of cellular energy is one of the fastest-growing areas of modern longevity medicine.
Exosomes: Japan as a leader in regenerative medicine
One of the biggest topics I encountered during my trip was exosomes. Japan is currently a major global leader in regenerative medicine, cellular communication, exosomes, and modern aesthetic technologies. In Japan, this direction is supported by a strong scientific background, research into cellular technologies, and an emphasis on quality, safety, and standardization. The existence of specialized professional and regulatory structures for products based on extracellular vesicles, which include exosomes, is also confirmed by the Japanese agency PMDA.
And this is where I understood one crucial thing: not all exosomes are the same. This word is used very frequently today. In reality, it is not enough to say that a product contains exosomes. The entire process is decisive. It depends on where the exosomes come from, what biological source they are derived from, their purity, concentration, and stability, how they are processed and stored, what bioactive substances they naturally contain, and whether the entire process takes place under controlled conditions.
Exosomes act as biological messengers between cells. They transfer information, signaling molecules, proteins, peptides, and other substances involved in cellular communication. This is precisely why they are considered one of the most promising topics in contemporary regenerative and aesthetic medicine.
In Japan, however, they do not just talk about the existence of exosomes. They talk primarily about their quality. Because the difference between a common product with exosomes and top-tier technology can be enormous. Just as not every collagen is the same, not every exosome is the same. For high-quality exosomes, precise processing, purity, stability, and the origin of the biological material are essential.
Japanese researchers pay great attention not only to the exosomes themselves but also to growth factors, placental extracts, and other bioactive substances that can be used in modern aesthetic and regenerative care. For placental extracts, gentle processing is crucial to preserve the quality of active ingredients. And that is exactly one of the reasons why Japanese technologies in the field of exosomes, placental extracts, and regenerative aesthetics are respected worldwide. It is not just a trend. It is a combination of science, technology, quality control, and long-term development.
Technology I tested myself
During my stay in Japan, I decided to undergo some of these technologies personally. I underwent an application based on exosomes and growth factors. At the same time, I underwent a unique treatment utilizing technology derived from the culture medium of human dental pulp cells.
It was this technology that fascinated me the most. Dental pulp cells are very interesting and active sources of biologically active substances. It might sound surprising, but dental pulp is highly monitored in regenerative medicine. It contains cells that can produce a wide spectrum of signaling molecules important for cellular communication.
Modern regenerative medicine increasingly shows that the future lies not just in the cells themselves, but also in the substances that cells create and pass on to their surroundings. These include growth factors, cytokines, peptides, exosomes, and other signaling molecules important for cellular communication. So-called culture medium can contain a complex of these biologically active substances.
That is why technology from human dental pulp cells is so interesting. It shows where modern aesthetic and regenerative medicine is heading: from a simple surface effect to working with cellular communication, regeneration, and tissue quality.
Beauty does not start only inside. It also needs the right care from the outside
Throughout all these meetings, one more essential topic caught my attention. Skin is not just a surface. Skin is a living organ. Just as it needs support from within, it also needs proper care from the outside.
We now know that skin quality is not influenced only by age. The quality of the cosmetics used, active ingredients, skin barrier protection, the consistency of home care, the method of professional treatment, technologies used in salon care, and the skin's ability to regenerate all play a major role.
Modern cosmetology is therefore increasingly focusing on supporting the natural functions of skin cells. It is not just about the immediate effect after a treatment. It is about long-term skin health. If the skin barrier is weakened, if the skin is chronically irritated, dehydrated, or long-term burdened by inappropriate care, it cannot respond well even to the best active ingredients.
That is why it is important not only what we consume internally, but also what cosmetics we use, what technologies we choose, and how we work with our skin. This is why I realized once again during my trip how important it is to combine quality cosmetics, professional treatments, modern technologies, active ingredients, skin barrier protection, and internal body care.
And this is why I am very happy that at byFEMME we can work with technologies and products that correspond to current trends in modern cosmetology and the philosophy of Inner Beauty. Because truly beautiful skin does not happen by accident. It is created by combining quality home care, professional treatment, properly selected technologies, and the healthy functioning of the organism.
Why one product or one procedure is not enough
After all the expert meetings, I became increasingly aware of one thing. The world of beauty today often seeks quick solutions. One supplement. One procedure. One ingredient. One treatment.
But the body does not function this way. Skin, immunity, digestion, energy, sleep, hormones, and regeneration are interconnected systems. If we want to talk about longevity, healthy aging, and beautiful skin, we must look at the person as a whole.
And that is precisely the philosophy that is very strong in Japan. Not to separate beauty from health. Not to separate the skin from the organism. Not to separate cosmetics from nutrition. Not to separate modern technology from basic prevention.
So where does beauty truly begin
After all the seminars, laboratories, training sessions, and personal experiences, I realized one fundamental thing. Not exosomes. Not Deazaflavin. Not autophagy. Not stem cells. Not the most modern technologies. On their own, they are not enough.
The most important thing is to create an environment in which our cells can function correctly. Because it is the cells that decide how we regenerate, how we age, how our skin looks, and how we feel.
That is where true longevity begins. That is where health begins. And that is also where true beauty begins.
I am happy and I thank Esthe Pro Labo very much for this opportunity, and I am grateful to be able to represent this brand throughout Europe.
And this is exactly the approach we want to bring into our salon: a combination of quality internal care, top-tier cosmetics, modern technologies, and a deeper understanding of how the human body, skin, and regeneration function.
Hana Olscher
Science Behind Beauty
Discover the Inner Beauty philosophy
Herbzyme 113 and Zakuro – fermented microbiome support